I will tell you that if I am in the car and it is running and my wife tries to unlock the passenger door, it usally won't. Also if I am in the car and it is not in park her fob wont open the door for her. It does the same for me. I don't recall other problems with opening doors. Now locking is a different story. Sometime I have to press the button 2 and sometimes 3 times to get it to lock. I find sometimes holding the button for 4-5 seconds does the trick, but it is annoying.

The system seams to have a few flaws, or as some in the computer world call them "features"