CR's MPG figures aren't from a lab or track, they are road conditions, and are somewhat variable. They use trained staff drivers and similar conditions to try to minimize variables, but it's not always identical or reproducable, like the EPA figures. I remember reading the full report on how they test vehicles, but couldn't find the link.

They do NOT drive for efficiency, but instead how most drivers would drive. A V-6 would be driven to take advantage of the engine, on the idea that if a buyer pays extra they would expect better performance. They don't floor it, but overall performance of the car is evaluated in the driving. Their numbers are probably more realistic to most people than the EPA's (and nearly every car getting lower numbers) but many get better, some may get worse. It's fair to say the standard Accord V-6 was driven the same as the Hybrid and can be used as a basis for comparison, but driving for efficiency in the standard might not yield you the same benefits as the Hybrid.