I have a actual Honda Accord Hybrid Service Manual for 2005-2006. Under the maintenance schedule they recommend replacing the spark plugs along with the timing belt at 105,000 miles. They refer me to page 4-25, however all this page shows is how to inspect the plugs. It does not give any direction as to how to replace them. I've look through some other pages, and as far as ignition coil module replacement, they essentially have you removing the plastic engine cover and then just pulling out the ICM's. I have not looked at my car personally, but perhaps they are fairly easy to get too.