w16,
At fueleconomy.gov, the Highlander V6 2WD has owners who average 18.9mpg, the best one getting 20.3mpg average. We're getting 29.8 with our V6 Hybrid 2WD. That's a 58% increase in mpg over 18.9. It's not apples to apples to compare an SUV to your Civic Hybrid, but comparing vehicles that are alike, a 58% increase is significant.
Of course, your mileage may vary. Just check out the mileage database to see where you might land depending on driving style, load, and environment. We're fortunate to live in Southern California where the weather is a bit more consistent (fortunate for THIS purpose, anyway... lol). but the mpg is down over late summer when we bought the car, even though the temp is only down from 80 to 60. For us, the purchase was worthwhile. Hopefully it can be for you too.
Rick