When mistakenly bought the 2 Gig SD card I tried using a Sandisk 6 in 1 reader as well. As I mentioned earlier, I had no luck with it. I'm now currently using a 4 Gig Compact Flash and using a Sandisk Compact Flash Card reader only, and its been working flawlessly. I have each album seperated into a different folder, so the heiarchy is pretty extensive, and even with that being said, it works like a champ...