I'm driving from Urbana, IL to Louisville, KY next weekend, a distance of about 235 miles. I have only about 500 miles on my new 2006 Honda Civic Hybrid, so I'm still well in my "break-in period". The car is set up as it was at the dealer (in regards to tire pressure, etc) and is stock. I intend to drive 9 mph over the speed limit with no stops, so I'll probably average about 73 mph. I don't intend to run the a/c, but only God knows how hot it will be that weekend!

So, what's your best bet? I'll post my actual mileage when I get back.