I think everyone here had a bad first tank. Mine was 45mpg. My second was 50mpg. My current one is reading 57.5mpg after 360 miles.
There are many, many threads on this forum with discussions of tips and techniques to improve your efficiency. Click around and read... you'll be hypermiling in no time :-p
As far as break-in goes, it's the same as for any car... don't rev too high and avoid speeding on the highway. After you've broken the car in, continue driving it that way
