I agree that it is expensive...at face value. But I should be getting about $4400 back in the form of a Federal and Colorado State Tax Credit in 2007. I am also getting the NAV (since my wife does home health care) which adds to the overall price.
Looking solely at MSRP (I imagine that the "gas onlys" are getting discounted more than the Hybrids), the EX Automatic with NAV is $20,560 plus Destination Charge. The HCH with NAV is $23,350 plus Destination Charge. So, the price difference is $2790. Factoring in my Tax Credit, the cost of the HCH is around $1610 less than an EX, although I lose the moonroof, but gain the Auto Climate Control. I am sure there are a few other things to gain and lose. This also comes out to only $1640 more than an LX Automatic.
So, although the immediate out of pocket is pretty high, after my 2006 tax return in 2007, it will work out to be a pretty darn good deal...and I'll save gas and pollute less...Especially compared to the Sub.

2005 Honda Odyssey EX-L RES & NAV - Desert Rock Metallic
2006 Honda Civic Hybrid NAV - Magnetic Pearl
2007 Toyota FJ Cruiser - Black Cherry (First Toyota, Third non-Honda)