A while back I saw a van hit a blown truck tire on the highway. Van was driving aggressive (over the limit) and apparently didn't see the tire in time. Ran over it and it lodged under the chassis, driver panicked and locked the brakes, van swerved side to side on 2 wheels with not traction because the tire lifted the van off the roadway and almost flipped. Bet they had to do some laundry when they got home.....

One of those new larger tires would definitely do some major damage to any vehicle, as you said.